Medicinal Chemistry of Bioactive Compounds and Green Chemistry

Professor Emeritus Dr. Somsak Ruchirawat Chulabhorn Graduate Institute / Chulabhorn Research Institute In summary, a novel synthetic method for the preparation of substituted indanes was successfully developed via the Lewis/Brønsted acid-mediated cyclization of the E-stilbenylmethanols followed by nucleophilic transfer from trialkylsilyl reagents. The reactions gave the products in good to excellent yields with excellent diastereocontrol;… (read more)