Archive for 2014

The Inhibitory Effects of Dietary and Medicinal Plants-derived Chemicals on Nitrated-Polycyclic Aromatic Hydrocarbon (nitro-PAH) Induced Oxidative Stress in Human Pulmonary Epithelial Cell Line (A549)

Dr. Jantamas Kanitwithayanun Chulabhorn Research Institute Traffic-related particulate pollution is a main source of exposure to mutagenic and carcinogenic compounds such as polycyclic aromatic hydrocarbons (PAHs) and nitro-PAHs. Epidemiological studies have demonstrated that exposure to these toxic air pollutions is associated with respiratory diseases and lung cancer. Nitro-PAHs are generated through incomplete combustion of fossil… (read more)

The Effects of Herbicide on Antibiotic Resistance Profile in Stenotrophomonas maltophilia, an Emerging Cause of Nosocomial Infections

Assoc. Prof. Dr. Paiboon Vattanaviboon Chulabhorn Research Institute Stenotrophomonas maltophilia MfsA (Smlt1083) is a multidrug efflux pump in the major facilitator superfamily (MFS). Deletion of mfsA renders the strain more susceptible to multiple structurally non-related drugs including paraquat, kanamycin, streptomycin, neomycin, norfloxacin, chloramphenicol and tetracycline. No alteration in the susceptibility levels of the delta-mfsA mutant… (read more)

Effects of Elevated Temperature Related to Heat/Oxidative Stress in Human Pathogen; Pseudomonas aeruginosa

Prof.Dr. Skorn Mongkolsuk Faculty of Science, Mahidol University and Chulabhorn Research Institute The Pseudomonas aeruginosa PAO1 thiol peroxidase homolog (Tpx) belongs to a family of enzymes implicated in the removal of toxic peroxides. We have shown the expression of tpx to be highly inducible with redox cycling/superoxide generators and diamide and weakly inducible with organic… (read more)

Effect of Climate Change on Environmental Factors and Incidence of Pathogenic Bacteria in Ang Sila Coastal Area and Pra-sae Estuary

Asst. Prof. Dr. Karaked Tedsree Faculty of Science, Burapha University This study aimed to determine the effect of climate change on environmental factors and incidence of pathogenic bacteria, namely Vibrio spp., in the Ang Sila Coastal Area and Pra-sae estuary. The results demonstrated that increases in rainfall and water temperature have led to increased amounts… (read more)

Development of High Efficient Photocatalysts for Benzene Degradation

Asst. Prof. Dr. Karaked Tedsree Faculty of Science, Burapha University This research focuses on the development of photocatalytic efficiency of nanotitanium dioxide for degradation of benzene contaminant in water. Titanium dioxide nanoparticles with different sizes were prepared by chemical precipitation method and sol-gel process. Silver-modified titanium dioxide nanoparticles (silver/titaniumdioxide nanoparticle) were prepared by chemical reduction… (read more)