Posts filed under โครงการวิจัย

The Molecular Effects of Herbicide Paraquat on Pathogenic Bacteria

Dr. Paiboon Vattanaviboon Chulabhorn Graduate Institute and Chulabhorn Research Institute The role of the nfuA gene encoding an iron-sulfur (Fe-S) cluster scaffold protein in the human pathogen, Pseudomonas aeruginosa, was investigated. The expression of nfuA was induced upon exposure to herbicide paraquat and other superoxide generators and thiol-depleting agent and was mediated by IscR, an… (read more)

Effect of Environmental Changes on Pseudomonas aeruginosa, a Causative Agent of Nosocomial Infection

Dr. Mayuree Fuangthong Chulabhorn Graduate Institute and Chulabhorn Research Institute Pseudomonas aeruginosa an opportunistic pathogen of humans that causes nosocomial infections in hospitalized patients, immunocompromised hosts and patients with burns as well as infecting those with cystic fibrosis. Among many virulence factors, its ability to survive oxidative stress is one of the important characteristics allowing… (read more)

Enhancing Performance of Lipase for Biodiesel Production by Cell Surface Displaying and Increased Thermostability

Dr. Suvit Loprasert Chulabhorn Graduate Institute and Chulabhorn Research Institute The organic solvent resistant lipase (Lipase A) producing Proteus sp. SW1 was isolated from the beer factory waste in Thailand. The enzyme was found to have characteristics suitable for biodiesel production. The gene encoding this Lipase A (lipA) was successfully cloned from the chromosome of… (read more)

Construction of Acinetobacter baylyi Producing the Organic Solvent-tolerant Lipase with a Broad Spectrum of Substrate Specificity

Asst.Prof.Dr. Jittima Charoenpanich Faculty of Science, Burapha University Lipases are commonly applied enzymes in biocatalysis and organic chemistry. They catalyze numerous reactions, recognize many substrates and exhibit high regioselectivity and enantiospecificity, characteristics that contribute to their wide application. The temperature and solvent stability as well as broad substrate specificity of lipases have regarded as the… (read more)

Investigation of Estrogenic and Estrogen-like Pollutant by Cell Technology Assay

Assoc. Prof. Dr. Weera Wongkham Faculty of Science, Chiang Mai University This research work aims at studying the existence of endocrine disruptors (ED) polluted in aqueous natural resources in which affect on living organism in Chiang Mai, northern Thailand. Targeting at using cellular technologies to screen and evaluate the bioactive effects and to quantify the… (read more)