The Inhibitory Effects of Dietary and Medicinal Plants-derived Chemicals on Nitrated-Polycyclic Aromatic Hydrocarbon (nitro-PAH) Induced Oxidative Stress in Human Pulmonary Epithelial Cell Line (A549)

Dr. Jantamas Kanitwithayanun Chulabhorn Research Institute Traffic-related particulate pollution is a main source of exposure to mutagenic and carcinogenic compounds such as polycyclic aromatic hydrocarbons (PAHs) and nitro-PAHs. Epidemiological studies have demonstrated that exposure to these toxic air pollutions is associated with respiratory diseases and lung cancer. Nitro-PAHs are generated through incomplete combustion of fossil… (read more)